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Pretransplantation Therapy with Azacitidine vs Induction Chemotherapy and Posttransplantation Outcome in Patients with MDS  Aaron T. Gerds, Ted A. Gooley,

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Presentation on theme: "Pretransplantation Therapy with Azacitidine vs Induction Chemotherapy and Posttransplantation Outcome in Patients with MDS  Aaron T. Gerds, Ted A. Gooley,"— Presentation transcript:

1 Pretransplantation Therapy with Azacitidine vs Induction Chemotherapy and Posttransplantation Outcome in Patients with MDS  Aaron T. Gerds, Ted A. Gooley, Elihu H. Estey, Frederick R. Appelbaum, H. Joachim Deeg, Bart L. Scott  Biology of Blood and Marrow Transplantation  Volume 18, Issue 8, Pages (August 2012) DOI: /j.bbmt Copyright © 2012 American Society for Blood and Marrow Transplantation Terms and Conditions

2 Figure 1 Overall survival after hematopoietic cell transplantation (HCT) according to pretransplantation therapy: azacitidine (AZA) vs induction chemotherapy (IC). Patients were censored at the last follow-up. The difference between AZA and IC was not significant at P = .24. Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © 2012 American Society for Blood and Marrow Transplantation Terms and Conditions

3 Figure 2 Nonrelapse mortality following hematopoietic cell transplantation (HCT) according to pretransplantation therapy: azacitidine (AZA) vs induction chemotherapy (IC). Patients were censored at the last follow-up. The difference between AZA and IC was not significant at P = .98. Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © 2012 American Society for Blood and Marrow Transplantation Terms and Conditions

4 Figure 3 Relapse after hematopoietic cell transplantation (HCT) according to pretransplantation therapy: azacitidine (AZA) vs induction chemotherapy (IC). Patients were censored at the last follow-up. The difference between AZA and IC was significant at P = .04. Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © 2012 American Society for Blood and Marrow Transplantation Terms and Conditions

5 Figure 4 Relapse-free survival (RFS) after HCT according to pretransplantation therapy: azacitidine (AZA) vs induction chemotherapy (IC). Patients were censored at the last follow-up. The difference between AZA and IC was not significant at P = .14. Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © 2012 American Society for Blood and Marrow Transplantation Terms and Conditions


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