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Translational Entropy and DNA Duplex Stability

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Presentation on theme: "Translational Entropy and DNA Duplex Stability"— Presentation transcript:

1 Translational Entropy and DNA Duplex Stability
Peter L. Privalov, Colyn Crane-Robinson  Biophysical Journal  Volume 114, Issue 1, Pages (January 2018) DOI: /j.bpj Copyright © 2017 Biophysical Society Terms and Conditions

2 Figure 1 Comparison of the partial molar heat capacities of 9-, 12-, and 15-basepair CG duplexes (in red) and the same length duplexes having AT pairs in the central region (in blue). All measurements are at the identical duplex concentration of 283 μM in 150 mM NaCl, 5 mM Na-Phosphate, pH 7.4. Reproduced from (10). To see this figure in color, go online. Biophysical Journal  , 15-20DOI: ( /j.bpj ) Copyright © 2017 Biophysical Society Terms and Conditions

3 Figure 2 The partial heat capacities of the three CG duplexes in 150 mM NaCl, 5 mM Na-phosphate, pH 7.4, calculated per mole of basepair. (Inset) Given here is the dependence of the excess enthalpy on the transition temperature, the slope of which gives the heat capacity increment (from (10)). Biophysical Journal  , 15-20DOI: ( /j.bpj ) Copyright © 2017 Biophysical Society Terms and Conditions


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