1. Flying Under the Radar: Immune Evasion by Group B Streptococcus
Adelle P. McFarland, Joshua J. Woodward 
Cell Host & Microbe 
Volume 20, Issue 1, Pages 4-6 (July 2016)
DOI: /j.chom
Copyright © 2016 Elsevier Inc. Terms and Conditions

2. Figure 1
Degradation of c-di-AMP by Group B Streptococcus Modulates Immune Responses
Degradation of extracellular c-di-AMP (upper right panel) by CdnP and NudP leads to the production of adenosine, which may act as an immunosuppressive agent by engaging G protein-coupled adenosine receptors on immune cells. Degradation of DNA scaffolds by the nuclease NucA allows GBS to evade killing by neutrophil extracellular traps (NETs). Degradation of c-di-AMP by CdnP limits STING activation (lower left and right panels); however, bacterial DNA sensed by cGAS still promotes STING activation via production of 2′3′-cGAMP.
Cell Host & Microbe  , 4-6DOI: ( /j.chom )
Copyright © 2016 Elsevier Inc. Terms and Conditions