Download presentation
Presentation is loading. Please wait.
Published byKari Oksanen Modified over 5 years ago
1
A high-fat challenge increases airway inflammation and impairs bronchodilator recovery in asthma
Lisa G. Wood, PhD, Manohar L. Garg, PhD, Peter G. Gibson, MBBS Journal of Allergy and Clinical Immunology Volume 127, Issue 5, Pages (May 2011) DOI: /j.jaci Copyright © 2011 American Academy of Allergy, Asthma & Immunology Terms and Conditions
2
Fig 1 In subjects with asthma, changes in lung function monitored over 4 hours after administration of bronchodilator and consumption of the high fat (AHF) and low fat (ALF) food challenges. A, Change in % predicted FEV1 (% predicted FEV1 at 2, 3, and 4 hours – % predicted FEV1 at 0 hour). B, Change in FEV1/FVC (FEV1/FVC at 2, 3, and 4 hours – FEV1/FVC at 0 hour). ∗P < .05, AHF versus baseline; †P < .05, ALF versus baseline; ‡P < .05, AHF versus ALF. Journal of Allergy and Clinical Immunology , DOI: ( /j.jaci ) Copyright © 2011 American Academy of Allergy, Asthma & Immunology Terms and Conditions
3
Fig 2 In subjects with asthma, changes in innate immune activity at 4 hours after administration of bronchodilator and consumption of the high fat (AHF) and low fat (ALF) food challenges. A, Fold change in induced sputum cell TLR4 mRNA expression. B, Change in induced sputum percent neutrophils. Journal of Allergy and Clinical Immunology , DOI: ( /j.jaci ) Copyright © 2011 American Academy of Allergy, Asthma & Immunology Terms and Conditions
Similar presentations
© 2025 SlidePlayer.com. Inc.
All rights reserved.