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The influence of synovial inflammation and hyperplasia on symptomatic outcomes up to 2 years post-operatively in patients undergoing partial meniscectomy 

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Presentation on theme: "The influence of synovial inflammation and hyperplasia on symptomatic outcomes up to 2 years post-operatively in patients undergoing partial meniscectomy "— Presentation transcript:

1 The influence of synovial inflammation and hyperplasia on symptomatic outcomes up to 2 years post-operatively in patients undergoing partial meniscectomy  C.R. Scanzello, A.S. Albert, E. DiCarlo, K.B. Rajan, V. Kanda, E.U. Asomugha, B.H. Swaim, J.N. Katz, S.R. Goldring, J.C. Richmond, B. McKeon  Osteoarthritis and Cartilage  Volume 21, Issue 9, Pages (September 2013) DOI: /j.joca Copyright © 2013 Osteoarthritis Research Society International Terms and Conditions

2 Fig. 1 Distribution of synovial histology scores in the three biopsy sites. (A) Lining hyperplasia, (B) vascularity, (C) inflammation, and (D) fibrosis were graded on H&E stained sections as described in Methods. Twenty-eight patients provided synovial biopsies from all three sites. The medial and lateral gutter biopsies were described as ipsilateral or contralateral to the meniscal tear in each individual. 0–2 on the x-axes represents the histologic grade (Table I). Osteoarthritis and Cartilage  , DOI: ( /j.joca ) Copyright © 2013 Osteoarthritis Research Society International Terms and Conditions

3 Fig. 2 Pre- and post-operative symptom scores in patients undergoing meniscectomy over 2 years, stratified by presence or absence of synovial inflammation. Questionnaires and surveys were administered to patients pre-operatively (pre-op), as well as at 16 weeks (wks), 1 year (yr) and 2 years post-operatively as described. Improvements in all measures except the SF-12® MCS sub-scores were observed after surgery. Patients with inflammation are indicated by red triangles, patients without are indicated by black circles. (A) Lysholm scores, (B) pain scale, (C) SF-12® PCS sub-scores, (D) SF-12® MCS sub-scores. Osteoarthritis and Cartilage  , DOI: ( /j.joca ) Copyright © 2013 Osteoarthritis Research Society International Terms and Conditions


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