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Published byCoralie St-Cyr Modified over 5 years ago
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Effects of antiplatelet agents in combination with endothelial cell seeding on small- diameter Dacron vascular graft performance in the canine carotid artery model Steven P. Schmidt, Ph.D., Timothy J. Hunter, M.S., Linda J. Falkow, M.S., M.Michelle Evancho, B.S., William V. Sharp, M.D. Journal of Vascular Surgery Volume 2, Issue 6, Pages (November 1985) DOI: / (85) Copyright © 1985 Society for Vascular Surgery and North American Chapter, International Society for Cardiovascular Surgery Terms and Conditions
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Fig. 1 Transmission electron micrograph of graft luminal endothelial cell from ibuprofen-treated dog demonstrating characteristic ultrastructural morphology of endothelial cell including micropinocytotic vesicles (arrowhead) and Weibel-Palade body (small arrow). (Original magnification, × 15,000.) Journal of Vascular Surgery 1985 2, DOI: ( / (85) ) Copyright © 1985 Society for Vascular Surgery and North American Chapter, International Society for Cardiovascular Surgery Terms and Conditions
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Fig. 2 Confluent endothelial cells from midgraft region of endothelial cell—seeded graft at 3 weeks postoperatively. (Original magnification, × 500.) Journal of Vascular Surgery 1985 2, DOI: ( / (85) ) Copyright © 1985 Society for Vascular Surgery and North American Chapter, International Society for Cardiovascular Surgery Terms and Conditions
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Fig. 3 Comparison of gross appearance between patent endothelial cell—seeded and nonseeded (control) 4 mm I.D. Dacron vascular grafts retrieved 5 weeks postoperatively from carotid arteries of dog treated with U-63557A (10 mg/kg/day). Note pannus ingrowth of endothelium across anastomoses of nonseeded graft. Endothelial cell—seeded graft lumen was 100% covered by endothelial cells and 100% thrombus-free. Journal of Vascular Surgery 1985 2, DOI: ( / (85) ) Copyright © 1985 Society for Vascular Surgery and North American Chapter, International Society for Cardiovascular Surgery Terms and Conditions
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