1. Meta-analysis Comparing CT Colonography, Air Contrast Barium Enema, and Colonoscopy 
Alan S. Rosman, MD, Mark A. Korsten, MD 
The American Journal of Medicine 
Volume 120, Issue 3, Pages e4 (March 2007)
DOI: /j.amjmed
Copyright © 2007 Elsevier Inc. Terms and Conditions

2. Figure 1
sROC curves of 2 hypothetical tests. The test in (A) has good discrimination as determined by 3 hypothetic studies with the following pairs of sensitivities and specificities: 95% and 85%, 97% and 83%, and 85% and 95%, respectively. The test in (B) has poor discrimination as determined by 3 studies with the following pairs of sensitivities and specificities: 40% and 60%, 55% and 55%, and 60% and 40%, respectively. The sROC curves were constructed, and the exact AUC, homogenous AUC, and Q* index can be calculated. The homogeneous AUC is an approximation of the exact AUC that is easier to calculate. The index Q* is the point of the sROC curve in which the sensitivity equals the specificity. A perfect test has an exact AUC, homogeneous AUC, and index Q* values equal to 1, whereas a “worthless” test will have values equal to 0.5. For the test in (A), the exact AUC, homogeneous AUC, and index Q* are 0.963, 0.964, and 0.910, respectively. For the test in (B), the exact AUC, homogeneous AUC, and index Q* are 0.522, 0.522, and 0.517, respectively.
The American Journal of Medicine  , e4DOI: ( /j.amjmed )
Copyright © 2007 Elsevier Inc. Terms and Conditions

3. Figure 2
sROC curve for CT colonography detecting polyps of any size; 95% CIs (dotted lines). 2D = 2-dimensional; 3D = 3-dimensional; CT = computed tomographic; BE = barium enema; AUC = area under the curve.
The American Journal of Medicine  , e4DOI: ( /j.amjmed )
Copyright © 2007 Elsevier Inc. Terms and Conditions

4. Figure 3
sROC curve for CT colonography detecting polyps greater than 5 mm; 95% CIs (dotted lines). 2D = 2-dimensional; 3D = 3-dimensional; CT = computed tomographic; BE = barium enema; AUC = area under the curve.
The American Journal of Medicine  , e4DOI: ( /j.amjmed )
Copyright © 2007 Elsevier Inc. Terms and Conditions

5. Figure 4
sROC curve for CT colonography detecting polyps greater than 10 mm; 95% CIs (dotted lines). 2D = 2-dimensional; 3D = 3-dimensional; CT = computed tomographic; BE = barium enema; AUC = area under the curve.
The American Journal of Medicine  , e4DOI: ( /j.amjmed )
Copyright © 2007 Elsevier Inc. Terms and Conditions

6. Figure 5
sROC curve for colonoscopy detecting polyps greater than 5 mm. AUC = area under the curve.
The American Journal of Medicine  , e4DOI: ( /j.amjmed )
Copyright © 2007 Elsevier Inc. Terms and Conditions

7. Figure 6
sROC curve for colonoscopy detecting polyps greater than 10 mm. AUC = area under the curve.
The American Journal of Medicine  , e4DOI: ( /j.amjmed )
Copyright © 2007 Elsevier Inc. Terms and Conditions