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Primary Lung Cancer Presenting with Gastrointestinal Tract Involvement: Clinicopathologic and Immunohistochemical Features in a Series of 18 Consecutive.

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Presentation on theme: "Primary Lung Cancer Presenting with Gastrointestinal Tract Involvement: Clinicopathologic and Immunohistochemical Features in a Series of 18 Consecutive."— Presentation transcript:

1 Primary Lung Cancer Presenting with Gastrointestinal Tract Involvement: Clinicopathologic and Immunohistochemical Features in a Series of 18 Consecutive Cases  Giulio Rossi, MD, PhD, Alessandro Marchioni, MD, Elena Romagnani, MD, Federica Bertolini, MD, Lucia Longo, MD, Alberto Cavazza, MD, Fausto Barbieri, MD  Journal of Thoracic Oncology  Volume 2, Issue 2, Pages (February 2007) DOI: /S (15)30037-X Copyright © 2007 International Association for the Study of Lung Cancer Terms and Conditions

2 FIGURE 1 Duodenum biopsy (A, case 16; hematoxylin–eosin staining, ×125; black arrows) and a small bowel resection (B, case 7; hematoxylin–eosin staining, ×125) showing large, undifferentiated tumor cells with infiltrative growth pattern around normal glands. A giant cell carcinoma (C, case 6; hematoxylin–eosin, ×120) component and a large cell carcinoma with rhabdoid variant (D, case 2; hematoxylin–eosin staining, ×120). Journal of Thoracic Oncology 2007 2, DOI: ( /S (15)30037-X) Copyright © 2007 International Association for the Study of Lung Cancer Terms and Conditions

3 FIGURE 2 Metastatic tumor cells from lung cancer showing TTF-1 nuclear immunostaining and CK7 cytoplasmic positivity on a duodenum biopsy (A and C, case 16; immunoperoxidase, ×125) and small bowel resection (B and D, case 7; immunoperoxidase, ×120). Journal of Thoracic Oncology 2007 2, DOI: ( /S (15)30037-X) Copyright © 2007 International Association for the Study of Lung Cancer Terms and Conditions

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