1. Maintenance metabolism alone cannot explain non‐division
Maintenance metabolism alone cannot explain non‐division Linear decomposition of the TI feedrate (f) from data in Fig 2A separated the division (Ψ/Yx/s) and maintenance terms (ms): . For the division term, the division rate (Ψ, units of 1/h · [number of new and existing cells]/[number of existing cells]) was calculated to be the slope after the lag ends (inset). For each pulsing system, the calculated yield (Yx/s, units of g DCW/mmol glucose · [number of new and existing cells]/[number of existing cells]) was constant and the extrapolated maintenance term (ms) was not significantly detected (ms = −0.1 ± 0.1 mmol/g/h for spin flask system and ms = 0.006 ± 0.1 mmol/g/h for the plate reader setup).
Karthik Sekar et al. Mol Syst Biol 2018;14:e8623
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