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Published byGuus van den Broek Modified over 5 years ago
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Response to Shen et al. The American Journal of Human Genetics
Kevin J. Galinsky, Gaurav Bhatia, Po-Ru Loh, Stoyan Georgiev, Sayan Mukherjee, Nick J. Patterson, Alkes L. Price The American Journal of Human Genetics Volume 99, Issue 5, Pages (November 2016) DOI: /j.ajhg Copyright © 2016 American Society of Human Genetics Terms and Conditions
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Figure 1 Signals of Selection from PC1 of the GERA and GERA-noAJ Datasets We display Manhattan plots for the natural-selection scan along PC1 in the entire GERA dataset (top panel; identical to Figure 6 in Galinsky et al.1) and the GERA-noAJ dataset (bottom panel). The signal at ADH1B remains genome-wide significant in the GERA-noAJ dataset (see text). We note that for SLC45A2 (MIM: ) and TLR6-TLR1-TLR10 (MIM: , , ), two loci previously known to be under selection, suggestive signals of selection in the GERA dataset (Table S4 in Galinsky et al.1) are now genome-wide significant in the GERA-noAJ dataset. The American Journal of Human Genetics , DOI: ( /j.ajhg ) Copyright © 2016 American Society of Human Genetics Terms and Conditions
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