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Gefitinib (IRESSA) in Patients of Asian Origin with Refractory Advanced Non-small Cell Lung Cancer: Subset Analysis from the ISEL Study  Alex Chang, MD,

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Presentation on theme: "Gefitinib (IRESSA) in Patients of Asian Origin with Refractory Advanced Non-small Cell Lung Cancer: Subset Analysis from the ISEL Study  Alex Chang, MD,"— Presentation transcript:

1 Gefitinib (IRESSA) in Patients of Asian Origin with Refractory Advanced Non-small Cell Lung Cancer: Subset Analysis from the ISEL Study  Alex Chang, MD, Purvish Parikh, MD, Sumitra Thongprasert, MD, Eng Huat Tan, MD, Reury-Perng Perng, MD, Domingo Ganzon, MD, Chih-Hsin Yang, MD, Chao-Jung Tsao, MD, Claire Watkins, MSc, Nick Botwood, MD, Nick Thatcher, FRCP  Journal of Thoracic Oncology  Volume 1, Issue 8, Pages (October 2006) DOI: /S (15) Copyright © 2006 International Association for the Study of Lung Cancer Terms and Conditions

2 FIGURE 1 Overall survival in (A) patients of Asian origin (B) patients of non-Asian origin. Journal of Thoracic Oncology 2006 1, DOI: ( /S (15) ) Copyright © 2006 International Association for the Study of Lung Cancer Terms and Conditions

3 FIGURE 2 Time to treatment failure (TTF) for patients of Asian origin receiving gefitinib versus placebo. Journal of Thoracic Oncology 2006 1, DOI: ( /S (15) ) Copyright © 2006 International Association for the Study of Lung Cancer Terms and Conditions

4 FIGURE 3 Mean change from baseline for quality of life (functional assessment of cancer therapy-lung [FACT-L] questionnaire) and disease-related symptoms (lung cancer subscale [LCS]) in patients of Asian origin. Journal of Thoracic Oncology 2006 1, DOI: ( /S (15) ) Copyright © 2006 International Association for the Study of Lung Cancer Terms and Conditions

5 FIGURE 4 One-year survival rates of patients treated with gefitinib in IRESSA Survival Evaluation in Lung Cancer (ISEL) and other studies in Asian patients. Journal of Thoracic Oncology 2006 1, DOI: ( /S (15) ) Copyright © 2006 International Association for the Study of Lung Cancer Terms and Conditions


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