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Remifentanil and cyclooxygenase inhibitors interactions in the minimum alveolar concentration of sevoflurane in the rat  J Benito, D Aguado, M.B. Abreu,

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Presentation on theme: "Remifentanil and cyclooxygenase inhibitors interactions in the minimum alveolar concentration of sevoflurane in the rat  J Benito, D Aguado, M.B. Abreu,"— Presentation transcript:

1 Remifentanil and cyclooxygenase inhibitors interactions in the minimum alveolar concentration of sevoflurane in the rat  J Benito, D Aguado, M.B. Abreu, J García-Fernández, I.A. Gómez de Segura  British Journal of Anaesthesia  Volume 105, Issue 6, Pages (December 2010) DOI: /bja/aeq241 Copyright © 2010 The Author(s) Terms and Conditions

2 Fig 1 Experimental design.
British Journal of Anaesthesia  , DOI: ( /bja/aeq241) Copyright © 2010 The Author(s) Terms and Conditions

3 Fig 2 Reduction of the MAC of sevoflurane at different times produced by remifentanil alone (control) or combined with paracetamol, metamizole, ketoprofen, and parecoxib given at two different time points (top, delayed administration; bottom, simultaneous administration; Fig. 1). Data are expressed as mean (sd), n=8. *Different from control group (repeated measures). ‡RMF-2 different from time RMF-1, same drug. ‡‡RMF-2 different from time RMF-1, same drug, in all drug groups. Significant at a P-value of <0.05. British Journal of Anaesthesia  , DOI: ( /bja/aeq241) Copyright © 2010 The Author(s) Terms and Conditions


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