1. Lifestyle and Physiological Factors Associated with Facial Wrinkling in Men and Women 
Merel A. Hamer, Luba M. Pardo, Leonie C. Jacobs, M. Arfan Ikram, Joop S. Laven, Manfred Kayser, Loes M. Hollestein, David A. Gunn, Tamar Nijsten 
Journal of Investigative Dermatology 
Volume 137, Issue 8, Pages (August 2017)
DOI: /j.jid
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2. Figure 1
Distribution of the digital wrinkle area percentages split by sex. The distribution of the facial wrinkle area percentage is skewed towards higher values for both sexes. The median wrinkle area percentage was higher in men than in women.
Journal of Investigative Dermatology  , DOI: ( /j.jid )
Copyright © 2017 The Authors Terms and Conditions

3. Figure 2
Boxplots of wrinkle area % per age group (1: <65 years old; 2: 65–75 years old; 3: ≥75 years old), split by sex. Men have statistically significant higher wrinkle area than women in the lowest and middle age group. Women have statistically significant higher wrinkle area than men in the highest age group.
Journal of Investigative Dermatology  , DOI: ( /j.jid )
Copyright © 2017 The Authors Terms and Conditions

4. Figure 3
Digital extraction of wrinkles. Non-skin parts (i.e., eyes, nostrils, and mouth) are masked and wrinkle area is measured in units of pixels. Left: female participant; right: male participant.
Journal of Investigative Dermatology  , DOI: ( /j.jid )
Copyright © 2017 The Authors Terms and Conditions