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Angiogenesis and the atherosclerotic carotid plaque: An association between symptomatology and plaque morphology  Mark J. McCarthy, FRCS(Ed), Ian M. Loftus,

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Presentation on theme: "Angiogenesis and the atherosclerotic carotid plaque: An association between symptomatology and plaque morphology  Mark J. McCarthy, FRCS(Ed), Ian M. Loftus,"— Presentation transcript:

1 Angiogenesis and the atherosclerotic carotid plaque: An association between symptomatology and plaque morphology  Mark J. McCarthy, FRCS(Ed), Ian M. Loftus, FRCS, Matt M. Thompson, MD, FRCS, Louise Jones, MRCPath, Nicholas J.M. London, MD, FRCS, Peter R.F. Bell, MD, FRCS, A.Ross Naylor, MD, FRCS, Nicholas P.J. Brindle, PhD  Journal of Vascular Surgery  Volume 30, Issue 2, Pages (August 1999) DOI: /S (99) Copyright © 1999 Society of Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

2 Fig. 1 Number of microvessels identified from plaques of symptomatic and asymptomatic patients. Values are medians and interquartile ranges (W = 262.5, P < .0004). Journal of Vascular Surgery  , DOI: ( /S (99) ) Copyright © 1999 Society of Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

3 Fig. 2 Carotid plaque neovessels at the medial border of the lipid core from a symptomatic patient. Journal of Vascular Surgery  , DOI: ( /S (99) ) Copyright © 1999 Society of Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

4 Fig. 3 Neovessels within the cap of an atherosclerotic plaque of the carotid artery. Journal of Vascular Surgery  , DOI: ( /S (99) ) Copyright © 1999 Society of Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

5 Fig. 4 Different neovessel morphology as viewed at 400× magnification. A, Irregular lobulated shaped vessel; B, flattened vessel. Journal of Vascular Surgery  , DOI: ( /S (99) ) Copyright © 1999 Society of Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

6 Fig. 5 Number of total plaque microvessels associated with plaque, rupture, hemorrhage, and necrosis. Values shown are medians and interquartile ranges. Journal of Vascular Surgery  , DOI: ( /S (99) ) Copyright © 1999 Society of Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

7 Fig. 6 Number of cap microvessels associated with plaque, rupture, hemorrhage, and necrosis. Values shown are medians and interquartile ranges. Journal of Vascular Surgery  , DOI: ( /S (99) ) Copyright © 1999 Society of Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

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