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BRAFV600E and NRASQ61R Homogeneity in Melanoma Tumors

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Presentation on theme: "BRAFV600E and NRASQ61R Homogeneity in Melanoma Tumors"— Presentation transcript:

1 BRAFV600E and NRASQ61R Homogeneity in Melanoma Tumors
Arnaud Uguen, Matthieu Talagas, Pascale Marcorelles, Marc De Braekeleer  Journal of Investigative Dermatology  Volume 136, Issue 1, Pages (January 2016) DOI: /JID Copyright © 2015 The Authors Terms and Conditions

2 Figure 1 Example of anti-NRASQ61R immunohistochemistry (clone SP174) in an NRASQ61R mutated melanoma. Different intensities of staining are seen at (a) low (scale bar = 5 mm) and high magnification with progression of the signal from (b) weak (scale bar = 0.1 mm), (c) moderate (scale bar = 0.1 mm) to (d) strong (scale bar = 0.1 mm) staining of tumor cells, supporting technical issues more than true biological heterogeneity. Journal of Investigative Dermatology  , DOI: ( /JID ) Copyright © 2015 The Authors Terms and Conditions


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