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Costimulatory molecules in the developing human gastrointestinal tract: A pathway for fetal allergen priming Catherine A. Jones, PhD, Gillian H.S. Vance, MRCP, Lynsey L. Power, Sylvia L.F. Pender, PhD, Thomas T. MacDonald, MRCPath, PhD, John O. Warner, MD Journal of Allergy and Clinical Immunology Volume 108, Issue 2, Pages (August 2001) DOI: /mai Copyright © 2001 Mosby, Inc. Terms and Conditions
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Fig. 1 Antigen-presenting cell markers and costimulatory molecules within human fetal gut. Immunohistochemistry was used to evaluate the expression of MHC class II (a ), CD14 (b ), CD68 (c ), CD20 (d ), CD83 (e ), CD40 (f ), and CD86 (g ). An isotype-matched control was always included (h ). Representative examples of a total of 25 different tissues are shown. Scale bar = 0.2 mm. Journal of Allergy and Clinical Immunology , DOI: ( /mai ) Copyright © 2001 Mosby, Inc. Terms and Conditions
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Fig. 2 T lymphocytes and costimulatory counterligands within human fetal gut. Immunohistochemistry was used to evaluate the expression of CD3 (a ), CD28 (b ), CD40L (c ), and CTLA-4 (d ). An isotype control was always included (e ). Representative examples of a total of 25 different tissues are shown. Scale bar = 0.2 mm. Journal of Allergy and Clinical Immunology , DOI: ( /mai ) Copyright © 2001 Mosby, Inc. Terms and Conditions
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