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The effects of aortic reconstruction and collagen impregnation of Dacron prostheses on the complement system  J.C.A. De Mol Van Otterloo, MD1, J.H. Van.

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Presentation on theme: "The effects of aortic reconstruction and collagen impregnation of Dacron prostheses on the complement system  J.C.A. De Mol Van Otterloo, MD1, J.H. Van."— Presentation transcript:

1 The effects of aortic reconstruction and collagen impregnation of Dacron prostheses on the complement system  J.C.A. De Mol Van Otterloo, MD1, J.H. Van Bockel, MD1, E.D. Ponfoort, E.J.P. Brommer, MD3, J. Hermans, PhD1, M.R. Daha, PhD2  Journal of Vascular Surgery  Volume 16, Issue 5, Pages (November 1992) DOI: / (92)90233-X Copyright © 1992 Society for Vascular Surgery and the North American Chapter, International Society for Cardiovascular Surgery Terms and Conditions

2 Fig. 1 The complement system. CH50 measures the combined level of C1–C9 activity. Journal of Vascular Surgery  , DOI: ( / (92)90233-X) Copyright © 1992 Society for Vascular Surgery and the North American Chapter, International Society for Cardiovascular Surgery Terms and Conditions

3 Fig. 2 Median percentage and 25% to 75% intervals of CH50(upper panel), C4 (second panel), factor B (third panel) in patients with a collagen-impregnated prosthesis (ci) compared with levels in patients with a nonimpregnated prosthesis (ni) before operation (day -1), during operation (day 0), and after operation (days 2, 10, and 90). Continuous lines between the time points represent collagen impregnated prostheses, broken lines represent nonimpregnated prostheses. P values between time points within prosthesis groups are shown together with lines. P values of differences between the prosthesis groups are shown at the top of each panel at the appropriate time point. Journal of Vascular Surgery  , DOI: ( / (92)90233-X) Copyright © 1992 Society for Vascular Surgery and the North American Chapter, International Society for Cardiovascular Surgery Terms and Conditions

4 Fig. 3 Median percentage and 25% to 75% intervals of C3a (upper panel) and median percentage of C3a/C3 fraction (lower panel) in patients with a collagen-impregnated prosthesis (ci) compared with levels in patients with a nonimpregnated prosthesis (ni) before operation (day -1), during operation (day 0), and after operation (days 2, 10, 90). Continuous lines between the time points represent collagen impregnated prostheses, broken lines represent nonimpregnated prostheses. P values between time points within prosthesis groups are shown together with lines. *No significant differences were observed. P values of differences between the prosthesis groups are shown at the top of each panel at the appropriate time point. Journal of Vascular Surgery  , DOI: ( / (92)90233-X) Copyright © 1992 Society for Vascular Surgery and the North American Chapter, International Society for Cardiovascular Surgery Terms and Conditions

5 Fig. 4 Median percentage and 25% to 75% intervals of CH50(upper panel), C4 (second panel), and factor B (third panel) in patients with a vascular procedures (v) compared with controls (c) before operation (day -1), during operation (day 0), and after operation (days 2, 10, and 90). Continuous lines between the time points represent controls, broken lines represent vascular patients. P values between time points within disease groups are shown together with lines. P values of differences between the prosthesis groups are shown at the top of each panel at the appropriate time point. Journal of Vascular Surgery  , DOI: ( / (92)90233-X) Copyright © 1992 Society for Vascular Surgery and the North American Chapter, International Society for Cardiovascular Surgery Terms and Conditions

6 Fig. 5 Median percentage and 25% to 75% intervals of C3a (upper panel) and median percentage of C3a/C3 fraction (lower panel) in patients with a vascular procedure (v) compared with controls (c) before operation (day -1), during operation (day 0), and after operation (days 2, 10, 90). Continuous lines between the time points represent controls, broken lines represent vascular patients, P values between time points within disease groups are shown together with lines. *No significant differences were observed. P values of differences between the prosthesis groups are shown at the top of each panel at the appropriate time point. Journal of Vascular Surgery  , DOI: ( / (92)90233-X) Copyright © 1992 Society for Vascular Surgery and the North American Chapter, International Society for Cardiovascular Surgery Terms and Conditions

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