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Denervation leads to volume regression in breast cancer

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Presentation on theme: "Denervation leads to volume regression in breast cancer"— Presentation transcript:

1 Denervation leads to volume regression in breast cancer
Elisabeth A. Kappos, Patricia E. Engels, Mathias Tremp, Patricia K. Sieber, Stefanie von Felten, Srinivas Madduri, Moritz Meyer zu Schwabedissen, Arne Fischmann, Dirk J. Schaefer, Daniel F. Kalbermatten  Journal of Plastic, Reconstructive & Aesthetic Surgery  Volume 71, Issue 6, Pages (June 2018) DOI: /j.bjps Copyright © 2018 British Association of Plastic, Reconstructive and Aesthetic Surgeons Terms and Conditions

2 Figure 1 1a and 1b – Image of surgical model with neurovascular fasciocutaneous flap after injection of tumor cells and nerve intact (a) and nerve cut (b). Journal of Plastic, Reconstructive & Aesthetic Surgery  , DOI: ( /j.bjps ) Copyright © 2018 British Association of Plastic, Reconstructive and Aesthetic Surgeons Terms and Conditions

3 Figure 2 Tumor volume (in mm3) by MRI with ingoing nerve intact and cut (denervation of the treated adipofascial flap) after 2 weeks and 8 weeks of observation. Journal of Plastic, Reconstructive & Aesthetic Surgery  , DOI: ( /j.bjps ) Copyright © 2018 British Association of Plastic, Reconstructive and Aesthetic Surgeons Terms and Conditions

4 Figure 3 MRI with contrast. Representative images with intact nerve (left column) and cut nerve (right column), a-d: at 2 weeks, e-h: at 8 weeks. Tumor marked with bold arrows. Tumor surrounding flap tissue indicated with small arrows in (a). Postoperative fluid collections marked by arrowheads in (b) and (e). Almost complete tumor regression marked by bold arrow in (h). Journal of Plastic, Reconstructive & Aesthetic Surgery  , DOI: ( /j.bjps ) Copyright © 2018 British Association of Plastic, Reconstructive and Aesthetic Surgeons Terms and Conditions

5 Figure 4 Tumor cross-sectional area (in mm2) by histology with ingoing nerve intact and cut (denervation of the treated adipofascial flap) after 2 weeks and 8 weeks of observation. Journal of Plastic, Reconstructive & Aesthetic Surgery  , DOI: ( /j.bjps ) Copyright © 2018 British Association of Plastic, Reconstructive and Aesthetic Surgeons Terms and Conditions


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