1. A B Supplementary Figure S1 PC3 cells Vehicle 3β-Adiol
Annexin V positive cells

2. Supplementary Figure S2
A B
3β–Adiol
ERE-Luciferase
Reporter
(LNCaP cells)

3. Supplementary Figure S3

4. Supplementary Figure S4

5. Supplementary Figure S5
A B
PC3 cells LNCaP cells C
PC3 cells

6. Supplementary Figure S6
chr6:
½ ERE
AP1
B C

7. Supplementary Figure S7
A B
C D
E F
G H

8. Supplementary Figure S8
A B
C D
E F