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Management of Prostate Cancer: Global Strategies

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Presentation on theme: "Management of Prostate Cancer: Global Strategies"— Presentation transcript:

1 Management of Prostate Cancer: Global Strategies
Antonio Alcaraz  European Urology Supplements  Volume 5, Issue 18, Pages (November 2006) DOI: /j.eursup Copyright © 2006 European Association of Urology Terms and Conditions

2 Fig. 1 Prognostic value of PSA velocity (PSAV) in detecting clinically significant pCA in an early detection setting [13]. Less-aggressive pCA was defined as stage <T2b, Gleason score <7; more-aggresive pCA was defined as stage ≥T2b, Gleason score ≥7. European Urology Supplements 2006 5, DOI: ( /j.eursup ) Copyright © 2006 European Association of Urology Terms and Conditions

3 Fig. 2 Comparison of percentage of positive surgical margins (PSM), nerve-sparing procedures, and pCA stages in patients treated with RP between 1993 and 2004 (ESPRE study). n=10,553 [24]. European Urology Supplements 2006 5, DOI: ( /j.eursup ) Copyright © 2006 European Association of Urology Terms and Conditions

4 Fig. 3 Five- and 10-yr survival outcomes after RP in patients with cT3a pCA (n=200) [28]. BPFS: biochemical progression-free survival; CPFS: clinical progression-free survival; CSS: cancer-specific survival; OS: overall survival. Mean follow-up=70.6 mo. European Urology Supplements 2006 5, DOI: ( /j.eursup ) Copyright © 2006 European Association of Urology Terms and Conditions

5 Fig. 4 Comparison of external beam radiotherapy (EBRT) and RP in terms of survival and disease progression after median follow-up of 67 mo [29]. European Urology Supplements 2006 5, DOI: ( /j.eursup ) Copyright © 2006 European Association of Urology Terms and Conditions

6 Fig. 5 Long-term risk for first and second skeletal-related events (SREs) in patients with metastatic pCA treated with zoledronic acid (ZA) compared with placebo [61]. European Urology Supplements 2006 5, DOI: ( /j.eursup ) Copyright © 2006 European Association of Urology Terms and Conditions


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