1. Cutaneous Angiosarcoma
Diagnosis
Cutaneous Angiosarcoma

2. Cutaneous Angiosarcoma
Classification
Idiopathic cutaneous angiosarcoma of head & neck
Lymphangiosarcoma arising in chronic lymphoedematous limbs
Post irradiation angiosarcoma

3. Cutaneous Angiosarcoma
Poorly circumscribed dermal tumours
Infiltrate subcutis
Multifocal distribution
Vascular channels lined by atypical endothelial cells
As architectural differentiation decreases, cytological atypia and cell size tend to increase

4. Cutaneous Angiosarcoma
Epithelioid cells may be prominent
Tumour cells may stain for CD31, CD34, Factor VIII-related antigen
EM may be useful in some cases
Distinction between malignant tumours showing blood vessel and lymphatic differentiation is often unclear & controversial