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Rat strain determines statin effect on intimal hyperplasia after carotid balloon injury
Alex Helkin, MD, Pratik Desai, MD, Ian Bailey, BA, David Bruch, MS, Kristopher G. Maier, PhD, Vivian Gahtan, MD Journal of Vascular Surgery Volume 63, Issue 2, Pages (February 2016) DOI: /j.jvs Copyright © Terms and Conditions
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Fig Summary of intima-media area ratios [intima/(intima + media), I/(I + M)]. There was no significant difference between the rats not receiving statins in any of the three groups or the lean Zucker (LZ) and obese Zucker (OZ) rats treated with statins. Statin-treated Sprague-Dawley (SD) rats showed a 25% decrease in intimal hyperplasia (IH; P < .05). ∗P < .05 compared with animals in the no-statin groups. Fluva, Fluvastatin; Simva, simvastatin. Journal of Vascular Surgery , DOI: ( /j.jvs ) Copyright © Terms and Conditions
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