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Massive Aquaresis After Tolvaptan Administration and Albumin Infusion in a Patient with Alcoholic Cirrhosis Charles Cho, MD, Joy L. Logan, MD, Yeong-Hau H. Lien, MD, PhD The American Journal of Medicine Volume 125, Issue 1, Pages e5-e6 (January 2012) DOI: /j.amjmed Copyright © 2012 Elsevier Inc. Terms and Conditions
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Figure 1 A, Hourly input (dash line) and urine output (solid line) after a single dose of tolvaptan given at time 0. The bar indicates 6-h intravenous 25% albumin infusion (50 mL/h). B, C, Time course of the change in serum sodium level and urine osmolality, respectively. The upward trend of serum sodium was leveled off after administration of intravenous hypotonic fluid. Tolvaptan caused a rapid decrease in urine osmolality. At 16 hours, urine osmolality increased as tolvaptan was weaned. The American Journal of Medicine , e5-e6DOI: ( /j.amjmed ) Copyright © 2012 Elsevier Inc. Terms and Conditions
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