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Quantification of phenotypes by genes and developmental stage

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Presentation on theme: "Quantification of phenotypes by genes and developmental stage"— Presentation transcript:

1 Quantification of phenotypes by genes and developmental stage
Quantification of phenotypes by genes and developmental stage ASchematic diagram depicting developmental timeline of iPSC‐derived cells included in analysis.B–FPercent distribution plots of (B) iPSC, (C) NSC, (D) astrocyte, (E) oligodendrocyte, and (F) neuronal phenotypes reported for genes linked to neurodegenerative, neurodevelopmental, or other (psychiatric and viral‐induced) disorders. Each data point represents a specific disease. One‐way analysis of variance (ANOVA) with Bonferroni multiple comparisons tests was performed (NDeg, n = 13; NDev, n = 15; Other, n = 3). Data are expressed as mean percentage ± s.e.m., *P < 0.05, **P < 0.01.GDistribution of phenotypes by pluripotent, progenitor, and postmitotic cell type for Alzheimer's disease (AD), Parkinson's (PD), Huntington's disease (HD), and Rett syndrome. Two‐way ANOVA with Tukey's multiple comparisons test was performed. *P < 0.05.HQuantification of number of genes observed by phenotype.IQuantification of observed phenotypes per gene. Ethan W Hollingsworth et al. EMBO Mol Med. 2017;emmm © as stated in the article, figure or figure legend

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