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K.D. Novakofski, R.M. Williams, L.J. Bonassar, L.A. Fortier 

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Presentation on theme: "K.D. Novakofski, R.M. Williams, L.J. Bonassar, L.A. Fortier "— Presentation transcript:

1 Early cartilage injury quantified and characterized with multiphoton microscopy imaging 
K.D. Novakofski, R.M. Williams, L.J. Bonassar, L.A. Fortier  Osteoarthritis and Cartilage  Volume 21, Pages S182-S183 (April 2013) DOI: /j.joca Copyright © Terms and Conditions

2 Figure 1 MPM of control and injured samples. Control samples typically contained few fluorescein-stained cells, while injured samples typically contained fluorescein-stained cells, autofluorescent structures, and cracks. Osteoarthritis and Cartilage  , S182-S183DOI: ( /j.joca ) Copyright © Terms and Conditions

3 Figure 2 3-D reconstruction of control and injured cartilage from n=1 sample. Each point represents a single dead chondrocyte. The total volume scanned was a checkerboard of volumetric Z-scans, with 10 images at 10 μm-step intervals. An image such as that in Figure 1 represents 1.6% of the area in Figure 2. Osteoarthritis and Cartilage  , S182-S183DOI: ( /j.joca ) Copyright © Terms and Conditions


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