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Identification of 2 new sesame seed allergens: Ses i 6 and Ses i 7

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1 Identification of 2 new sesame seed allergens: Ses i 6 and Ses i 7
Kirsten Beyer, MD, Galina Grishina, MS, Ludmilla Bardina, MS, Hugh A. Sampson, MD  Journal of Allergy and Clinical Immunology  Volume 119, Issue 6, Pages (June 2007) DOI: /j.jaci Copyright © 2007 American Academy of Allergy, Asthma & Immunology Terms and Conditions

2 Fig 1 Shown is the alignment for the newly identified sesame seed allergens Ses i 6 and Ses i 7 with know allergens of peanut (Ara h 3), walnut (Jug r 4), and hazelnut (Cor a 9) by using Vector NTI Advance. All aligned allergens belong to the 11 S globulins. Journal of Allergy and Clinical Immunology  , DOI: ( /j.jaci ) Copyright © 2007 American Academy of Allergy, Asthma & Immunology Terms and Conditions

3 Fig 2 The recombinant proteins Ses i 6 and Ses i 7 were separated on SDS-PAGE and transferred to Immobilon-P membranes. Lane 1 shows the molecular weight (MW) markers, lane 2 shows the Coomassie Blue stain for total protein analysis, lanes 3 to 27 show immunolabeling with sera from 24 patients with sesame seed allergy, and lanes 28 and 29 show the atopic and nonatopic controls, respectively. Journal of Allergy and Clinical Immunology  , DOI: ( /j.jaci ) Copyright © 2007 American Academy of Allergy, Asthma & Immunology Terms and Conditions

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