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Early left ventricular regional contractile impairment in chronic mitral regurgitation occurs in a consistent, heterogeneous pattern  Hersh S. Maniar,

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Presentation on theme: "Early left ventricular regional contractile impairment in chronic mitral regurgitation occurs in a consistent, heterogeneous pattern  Hersh S. Maniar,"— Presentation transcript:

1 Early left ventricular regional contractile impairment in chronic mitral regurgitation occurs in a consistent, heterogeneous pattern  Hersh S. Maniar, MD, Beckah D. Brady, BS, Urvi Lee, PhD, Brian P. Cupps, PhD, Julia Kar, PhD, Kathleen M. Wallace, MSW, Michael K. Pasque, MD  The Journal of Thoracic and Cardiovascular Surgery  Volume 148, Issue 4, Pages (October 2014) DOI: /j.jtcvs Copyright © 2014 The American Association for Thoracic Surgery Terms and Conditions

2 Figure 1 Images from (A and B) end-diastole and (C and D) end-systole, demonstrating deformations of tag lines during systole. The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /j.jtcvs ) Copyright © 2014 The American Association for Thoracic Surgery Terms and Conditions

3 Figure 2 For each patient, the heart was registered to a standard 18-region finite element mesh, and displacements were computed at the intersection points of the tag surfaces. Model-predicted displacements and strains were computed from a least squares fitting of the measured displacement data. The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /j.jtcvs ) Copyright © 2014 The American Association for Thoracic Surgery Terms and Conditions

4 Figure 3 Global left ventricular function, as assessed by global myocardial circumferential and longitudinal strains, compared with normal controls. LV, Left ventricular; MR, mitral regurgitation. The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /j.jtcvs ) Copyright © 2014 The American Association for Thoracic Surgery Terms and Conditions

5 Figure 4 Regional ventricular function among patients with mitral regurgitation, assessed by multiparametric z-score analysis. The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /j.jtcvs ) Copyright © 2014 The American Association for Thoracic Surgery Terms and Conditions


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