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Altered gait mechanics and elevated serum pro-inflammatory cytokines in asymptomatic patients with MRI evidence of knee cartilage loss  S.N. Edd, J. Favre,

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Presentation on theme: "Altered gait mechanics and elevated serum pro-inflammatory cytokines in asymptomatic patients with MRI evidence of knee cartilage loss  S.N. Edd, J. Favre,"— Presentation transcript:

1 Altered gait mechanics and elevated serum pro-inflammatory cytokines in asymptomatic patients with MRI evidence of knee cartilage loss  S.N. Edd, J. Favre, K. Blazek, P. Omoumi, J.L. Asay, T.P. Andriacchi  Osteoarthritis and Cartilage  Volume 25, Issue 6, Pages (June 2017) DOI: /j.joca Copyright © 2017 Osteoarthritis Research Society International Terms and Conditions

2 Fig. 1 Examples of MRI evidence of (a) partial-thickness cartilage loss (between arrows) and (b) full-thickness cartilage loss (between arrows) and bone marrow edema (arrowhead). Osteoarthritis and Cartilage  , DOI: ( /j.joca ) Copyright © 2017 Osteoarthritis Research Society International Terms and Conditions

3 Fig. 2 Stance knee flexion angle (a) and flexion moment (b) for Pre-OA (n = 52; red solid) and Control (n = 26; blue dashed) groups. Error bars represent one standard deviation on both sides of the mean. *Indicates Benjamini–Hochberg significance with α = 0.05. Osteoarthritis and Cartilage  , DOI: ( /j.joca ) Copyright © 2017 Osteoarthritis Research Society International Terms and Conditions

4 Fig. 3 Median and quartile ranges of TNFα serum concentration in Pre-OA (n = 47, mean of 2 measures per subject) and Control (n = 24, mean of 2 measures per subject) subjects. *Indicates bootstrap t-test significant difference between groups, P < 0.05. Osteoarthritis and Cartilage  , DOI: ( /j.joca ) Copyright © 2017 Osteoarthritis Research Society International Terms and Conditions


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