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Synergism Between Keratinocyte Growth Factor and Carboxymethyl Chitosan Reduces Pericardial Adhesions  Jackson B. Lopes, MD, PhD, Luis Alberto O. Dallan,

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Presentation on theme: "Synergism Between Keratinocyte Growth Factor and Carboxymethyl Chitosan Reduces Pericardial Adhesions  Jackson B. Lopes, MD, PhD, Luis Alberto O. Dallan,"— Presentation transcript:

1 Synergism Between Keratinocyte Growth Factor and Carboxymethyl Chitosan Reduces Pericardial Adhesions  Jackson B. Lopes, MD, PhD, Luis Alberto O. Dallan, MD, PhD, Luiz Felipe P. Moreira, MD, PhD, Sérgio P. Campana Filho, PhD, Paulo S. Gutierrez, MD, PhD, Luiz Augusto F. Lisboa, MD, PhD, Sergio Almeida de Oliveira, MD, PhD, Noedir Antonio G. Stolf, MD, PhD  The Annals of Thoracic Surgery  Volume 90, Issue 2, Pages (August 2010) DOI: /j.athoracsur Copyright © 2010 The Society of Thoracic Surgeons Terms and Conditions

2 Fig 1 Adhesion tenacity score. Posthoc Bonferroni-Dunn test: * = p < 0.01 versus control, KGF and NOCCts groups; † = p < 0.05 versus control. (KGF = keratinocyte growth factor; NOCCts = thermal sterile N,O-carboxymethyl chitosan.) The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2010 The Society of Thoracic Surgeons Terms and Conditions

3 Fig 2 Dissection time spent in adhesiolysis. Posthoc Bonferroni-Dunn test: * = p < versus control. (KGF = keratinocyte growth factor; NOCCts = thermal sterile N,O-carboxymethyl chitosan.) The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2010 The Society of Thoracic Surgeons Terms and Conditions

4 Fig 3 Amount of sharp dissection used in adhesiolysis . Posthoc Bonferroni-Dunn test: * = p < 0,001 versus control. (KGF = keratinocyte growth factor; NOCCts = thermal sterile N,O-carboxymethyl chitosan.) The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2010 The Society of Thoracic Surgeons Terms and Conditions

5 Fig 4 Immunostaining with anticytokeratin AE1/AE3 monoclonal antibody used to identify the mesothelial cells. The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2010 The Society of Thoracic Surgeons Terms and Conditions


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