1. Bellwork: 2/15 Put your phone up  Week 2/11 - 2/15
Describe the structure of DNA.
How do the nitrogenous bases pair?
What makes up a nucleotide?

2. Today:
Bellwork
Finish Video
Unit 5, Part 2 Notes
Start DNA POGIL

3. Materials
Unit Book

4. This Week: Monday: BioTech Lab Prep Tuesday: BioTech Lab
Wednesday: Pt. 1 Notes & Video
Friday: Pt. 2 Notes

5. Homework
Quiz
Due

6. Unit V: DNA & Molecular Genetics

7. Part 1I: DNA Discovery & Replication

8. Discovery of DNA

9. Erwin Chargaff
1950s
Contribution: Discovered the 1:1 ratio of base pairing (Chargaff’s Rule)
G=C
T=A

10. Rosalind Franklin
1950s
Contribution: Used x- ray diffraction on DNA molecules to discover its helical shape

11. Maurice Wilkins
1950s
Contribution: Deputy director of Franklin’s lab. Responsible for “taking” Franklin’s x- rays & showing them to Watson & Crick

12. Watson & Crick
1950s
Contribution: Used Franklin’s x-rays to develop the 1st double- helix model of DNA

13. DNA Replication

14. Vocab Review!

15. Replication Watson & Crick
Discovered DNA structure (kind of…not really…)
Revealed how replication works
Each DNA strand provides the information for complementary strand because of base pairing rules
A – T
G - C

16. When does DNA replication occur?

17. Where does DNA replication occur?

18. Cell Cycle

19. Replication New DNA made by the enzyme DNA polymerase
During DNA replication, each strand of the original DNA is used as the template
DNA polymerase synthesizes the complementary new strand
DNA replication is considered semi-conservative. WHY?
Keeps one original strand & makes one new strand

20. Activity!
Draw a diagram using two different colors of DNA replication for 3 rounds.

21. Think!
What would your diagram look like if it were conservative?

22. Bio Facts!
The human body has about 1 trillion cells that contain the 46 chromosomes in which DNA is stored.
If all of the DNA in one human cell were stretched end to end, it would form a line about 1.8 M long.
The DNA that makes up a single human chromosome might be made up of more than 250 million nucleotides.

23. Answer Questions in Note Guide