Presentation is loading. Please wait.

Presentation is loading. Please wait.

Clinical Significance of Serum Vascular Endothelial Growth Factor in Malignant Pleural Mesothelioma  Akihiro Yasumitsu, MD, Chiharu Tabata, MD, PhD, Rie.

Published byみいか のあき Modified over 5 years ago

Similar presentations

Presentation on theme: "Clinical Significance of Serum Vascular Endothelial Growth Factor in Malignant Pleural Mesothelioma  Akihiro Yasumitsu, MD, Chiharu Tabata, MD, PhD, Rie."— Presentation transcript:

1 Clinical Significance of Serum Vascular Endothelial Growth Factor in Malignant Pleural Mesothelioma 
Akihiro Yasumitsu, MD, Chiharu Tabata, MD, PhD, Rie Tabata, MD, PhD, Noriko Hirayama, MD, Aki Murakami, MD, Shusai Yamada, MD, Takayuki Terada, MD, Shinichiro Iida, MD, Kunihiro Tamura, MD, Kazuya Fukuoka, MD, PhD, Kozo Kuribayashi, MD, PhD, Takashi Nakano, MD, PhD  Journal of Thoracic Oncology  Volume 5, Issue 4, Pages (April 2010) DOI: /JTO.0b013e3181d2f008 Copyright © 2010 International Association for the Study of Lung Cancer Terms and Conditions

2 FIGURE 1 Sensitivity and specificity of serum VEGF for distinguishing patients with MPM from non-MPM subjects. An analysis that included 51 patients with MPM and 42 non-MPM subjects with a history of asbestos exposure revealed an area under the curve of (95% confidence interval, –0.9245). At a cutoff value of 460 pg/ml, the diagnostic sensitivity was 70.6%, and the specificity was 88.1%. Journal of Thoracic Oncology 2010 5, DOI: ( /JTO.0b013e3181d2f008) Copyright © 2010 International Association for the Study of Lung Cancer Terms and Conditions

3 FIGURE 2 Serum VEGF levels in patients with MPM and non-MPM subjects. (A) Serum VEGF levels in non-MPM subjects versus those in patients with MPM were measured as described in Materials and Methods. (B) Serum VEGF levels in patients with MPM divided into four stages are shown. The nonparametric Mann-Whitney U test (A) or the nonparametric Kruskal-Wallis test followed by the Mann-Whitney U test (B) was used. The p values less than 0.05 were considered significant. The horizontal bars represent the mean value of each group. The cutoff value is shown as a horizontal line. Journal of Thoracic Oncology 2010 5, DOI: ( /JTO.0b013e3181d2f008) Copyright © 2010 International Association for the Study of Lung Cancer Terms and Conditions

4 FIGURE 3 Survival of MPM subjects according to serum VEGF levels Estimates of the probability of survival were calculated using the Kaplan-Meier method and compared using the log-rank test. Journal of Thoracic Oncology 2010 5, DOI: ( /JTO.0b013e3181d2f008) Copyright © 2010 International Association for the Study of Lung Cancer Terms and Conditions

Download ppt "Clinical Significance of Serum Vascular Endothelial Growth Factor in Malignant Pleural Mesothelioma  Akihiro Yasumitsu, MD, Chiharu Tabata, MD, PhD, Rie."

Similar presentations

Su K. Metcalfe, MD, MPH, Michael T

Su K. Metcalfe, MD, MPH, Michael T
Pleurectomy/Decortication, Hyperthermic Pleural Lavage with Povidone-Iodine Followed by Adjuvant Chemotherapy in Patients with Malignant Pleural Mesothelioma 

Pleurectomy/Decortication, Hyperthermic Pleural Lavage with Povidone-Iodine Followed by Adjuvant Chemotherapy in Patients with Malignant Pleural Mesothelioma 
Primary Signet-Ring Carcinoma (SRC) of the Lung: A Population-Based Epidemiologic Study of 262 Cases with Comparison to Adenocarcinoma of the Lung  Sai-Hong.

Primary Signet-Ring Carcinoma (SRC) of the Lung: A Population-Based Epidemiologic Study of 262 Cases with Comparison to Adenocarcinoma of the Lung  Sai-Hong.
Outcome for Patients with Malignant Pleural Mesothelioma Referred for Trimodality Therapy in Western Australia  Arman Hasani, MBBS, FRACP, John M. Alvarez,

Outcome for Patients with Malignant Pleural Mesothelioma Referred for Trimodality Therapy in Western Australia  Arman Hasani, MBBS, FRACP, John M. Alvarez,
Combination of Mesothelin and CEA Significantly Improves the Differentiation between Malignant Pleural Mesothelioma, Benign Asbestos Disease, and Lung.

Combination of Mesothelin and CEA Significantly Improves the Differentiation between Malignant Pleural Mesothelioma, Benign Asbestos Disease, and Lung.
Carcinoma NOS is a Common Histologic Diagnosis and is Increasing in Proportion Among Non-small Cell Lung Cancer Histologies  Sai-Hong Ignatius Ou, MD,

Carcinoma NOS is a Common Histologic Diagnosis and is Increasing in Proportion Among Non-small Cell Lung Cancer Histologies  Sai-Hong Ignatius Ou, MD,
Phase II Study of Gefitinib, an Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor (EGFR-TKI), and Celecoxib, a Cyclooxygenase-2 (COX-2) Inhibitor,

Phase II Study of Gefitinib, an Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor (EGFR-TKI), and Celecoxib, a Cyclooxygenase-2 (COX-2) Inhibitor,
Significance of the Number of Positive Lymph Nodes in Resected Non-small Cell Lung Cancer  Takayuki Fukui, MD, Shoichi Mori, MD, Kohei Yokoi, MD, Tetsuya.

Significance of the Number of Positive Lymph Nodes in Resected Non-small Cell Lung Cancer  Takayuki Fukui, MD, Shoichi Mori, MD, Kohei Yokoi, MD, Tetsuya.
Liver Metastasis Is Associated with Poor Progression-Free Survival in Patients with Non–Small Cell Lung Cancer Treated with Nivolumab  Tomoko Funazo,

Liver Metastasis Is Associated with Poor Progression-Free Survival in Patients with Non–Small Cell Lung Cancer Treated with Nivolumab  Tomoko Funazo,
Zachary S. Morris, MD, PhD, Donald M. Cannon, MD, Brett A

Zachary S. Morris, MD, PhD, Donald M. Cannon, MD, Brett A
Prognostic Significance of the Number of Lymph Nodes Removed at Lobectomy in Stage IA Non-small Cell Lung Cancer  Sai-Hong Ignatius Ou, MD, PhD, Jason.

Prognostic Significance of the Number of Lymph Nodes Removed at Lobectomy in Stage IA Non-small Cell Lung Cancer  Sai-Hong Ignatius Ou, MD, PhD, Jason.
ALK FISH and IHC: You Cannot Have One without the Other

ALK FISH and IHC: You Cannot Have One without the Other
Phase II Trial with Carboplatin and Bendamustine in Patients with Extensive Stage Small-Cell Lung Cancer  Wolf Köster, MD, Andrea Heider, MD, Norbert.

Phase II Trial with Carboplatin and Bendamustine in Patients with Extensive Stage Small-Cell Lung Cancer  Wolf Köster, MD, Andrea Heider, MD, Norbert.
Prognostic Significance of C-Reactive Protein and Smoking in Patients with Advanced Non-small Cell Lung Cancer Treated with First-Line Palliative Chemotherapy 

Prognostic Significance of C-Reactive Protein and Smoking in Patients with Advanced Non-small Cell Lung Cancer Treated with First-Line Palliative Chemotherapy 
Pleurectomy/Decortication, Hyperthermic Pleural Lavage with Povidone-Iodine Followed by Adjuvant Chemotherapy in Patients with Malignant Pleural Mesothelioma 

Pleurectomy/Decortication, Hyperthermic Pleural Lavage with Povidone-Iodine Followed by Adjuvant Chemotherapy in Patients with Malignant Pleural Mesothelioma 
Validation of the Stage Groupings in the Eighth Edition of the TNM Classification for Lung Cancer  Xizhao Sui, MD, Wei Jiang, MD, Haiqing Chen, MD, Fan.

Validation of the Stage Groupings in the Eighth Edition of the TNM Classification for Lung Cancer  Xizhao Sui, MD, Wei Jiang, MD, Haiqing Chen, MD, Fan.
Incidence and Survival of Malignant Pleural Mesothelioma in Norway: A Population- Based Study of 1686 Cases  Åslaug Helland, MD, PhD, Steinar Solberg,

Incidence and Survival of Malignant Pleural Mesothelioma in Norway: A Population- Based Study of 1686 Cases  Åslaug Helland, MD, PhD, Steinar Solberg,
Susan C. Scott, MD, Nathan A. Pennell, MD, PhD 

Susan C. Scott, MD, Nathan A. Pennell, MD, PhD 
Low ERCC1 Expression in Malignant Pleural Mesotheliomas Treated with Cisplatin and Vinorelbine Predicts Prolonged Progression-Free Survival  Zarah Glad.

Low ERCC1 Expression in Malignant Pleural Mesotheliomas Treated with Cisplatin and Vinorelbine Predicts Prolonged Progression-Free Survival  Zarah Glad.
IA05.01 Lung Cancer Cases Journal of Thoracic Oncology

IA05.01 Lung Cancer Cases Journal of Thoracic Oncology

Similar presentations

Ads by Google