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Immunohistochemical Abnormalities of Fibrillin in Cardiovascular Tissues in Marfan’s Syndrome  Kirk J Fleischer, MD, Hossein C Nousari, MD, Grant J Anhalt,

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Presentation on theme: "Immunohistochemical Abnormalities of Fibrillin in Cardiovascular Tissues in Marfan’s Syndrome  Kirk J Fleischer, MD, Hossein C Nousari, MD, Grant J Anhalt,"— Presentation transcript:

1 Immunohistochemical Abnormalities of Fibrillin in Cardiovascular Tissues in Marfan’s Syndrome 
Kirk J Fleischer, MD, Hossein C Nousari, MD, Grant J Anhalt, MD, Christopher D Stone, MD, John C Laschinger, MD  The Annals of Thoracic Surgery  Volume 63, Issue 4, Pages (April 1997) DOI: /S (97)

2 Fig. 1 Immunofluorescent Texas red sulfanyl chloride staining of fibrillin in human aortic valve leaflet: normal leaflet from patient without Marfan’s syndrome. (Original magnification, ×400.) The Annals of Thoracic Surgery  , DOI: ( /S (97) )

3 Fig. 2 Immunofluorescent Texas red sulfanyl chloride staining of fibrillin in human aortic valve leaflet: leaflet from patient with Marfan’s syndrome shows severe fragmentation of fibrillin and markedly reduced quantity and homogeneity of these elastin-associated microfibrils. (Original magnification, ×400.) The Annals of Thoracic Surgery  , DOI: ( /S (97) )

4 Fig. 3 Immunofluorescent Texas red sulfanyl chloride staining of fibrillin in human aortic valve leaflet: leaflet from patient with Marfan’s syndrome shows moderate fragmentation of fibrillin. (Original magnification, ×400.) The Annals of Thoracic Surgery  , DOI: ( /S (97) )


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