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Involvement of p53 and p16 Tumor Suppressor Genes in Recessive Dystrophic Epidermolysis Bullosa-Associated Squamous Cell Carcinoma  Jack L. Arbiser, Chun-Yang.

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Presentation on theme: "Involvement of p53 and p16 Tumor Suppressor Genes in Recessive Dystrophic Epidermolysis Bullosa-Associated Squamous Cell Carcinoma  Jack L. Arbiser, Chun-Yang."— Presentation transcript:

1 Involvement of p53 and p16 Tumor Suppressor Genes in Recessive Dystrophic Epidermolysis Bullosa-Associated Squamous Cell Carcinoma  Jack L. Arbiser, Chun-Yang Fan, Xiaobo Su, Beth O. Van Emburgh, Francesca Cerimele, Mark Steven Miller, Jeff Harvell, M. Peter Marinkovich  Journal of Investigative Dermatology  Volume 123, Issue 4, Pages (October 2004) DOI: /j X x Copyright © 2004 The Society for Investigative Dermatology, Inc Terms and Conditions

2 Figure 1 Promoter methylation of p16ink4a in SCC samples. The number above the lanes represents the tumor number. Specimens 1–3 revealed no p16ink4 hypermethylation, thus were not included. Lanes labelled U represent p16 unmethylated-specific primer; lanes labeled M, methylated-specific primer. Journal of Investigative Dermatology  , DOI: ( /j X x) Copyright © 2004 The Society for Investigative Dermatology, Inc Terms and Conditions


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