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CD34+ Cell Selection versus Reduced-Intensity Conditioning and Unmodified Grafts for Allogeneic Hematopoietic Cell Transplantation in Patients Age >50.

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Presentation on theme: "CD34+ Cell Selection versus Reduced-Intensity Conditioning and Unmodified Grafts for Allogeneic Hematopoietic Cell Transplantation in Patients Age >50."— Presentation transcript:

1 CD34+ Cell Selection versus Reduced-Intensity Conditioning and Unmodified Grafts for Allogeneic Hematopoietic Cell Transplantation in Patients Age >50 Years with Acute Myelogenous Leukemia and Myelodysplastic Syndrome   Pere Barba, Rodrigo Martino, Qin Zhou, Christina Cho, Hugo Castro-Malaspina, Sean Devlin, Albert Esquirol, Sergio Giralt, Ann A. Jakubowski, Dolores Caballero, Molly Maloy, Esperanza B. Papadopoulos, José Luís Piñana, María Laura Fox, Francisco J. Márquez- Malaver, David Valcárcel, Carlos Solano, Lucía López-Corral, Jorge Sierra, Miguel-Angel Perales  Biology of Blood and Marrow Transplantation  Volume 24, Issue 5, Pages (May 2018) DOI: /j.bbmt Copyright © 2017 The American Society for Blood and Marrow Transplantation Terms and Conditions

2 Figure 1 Probabilities of OS (A) and RFS (B) according to transplantation approach. Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © 2017 The American Society for Blood and Marrow Transplantation Terms and Conditions

3 Figure 2 Probability of CRFS according to transplantation approach.
Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © 2017 The American Society for Blood and Marrow Transplantation Terms and Conditions

4 Figure 3 Cumulative incidence of NRM (A) and relapse (B) according to transplantation approach. Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © 2017 The American Society for Blood and Marrow Transplantation Terms and Conditions

5 Figure 4 Cumulative incidences of acute (A) and chronic (B) GVHD.
Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © 2017 The American Society for Blood and Marrow Transplantation Terms and Conditions

6 Figure 5 Probability of OS (A) and CRFS (B) according to transplantation approach and comorbidity burden. Patients were categorized into 4 subgroups: TCD and HCT-CI 0 to 2 (n = 100), TCD and HCT-CI ≥3 (n = 104), RIC and HCT-CI 0 to 2 (n = 94), and RIC and HCT-CI ≥3 (n = 58). Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © 2017 The American Society for Blood and Marrow Transplantation Terms and Conditions


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