1. DO NOW What is the function of DNA?
What is the “one gene-one protein” theory?
GRAB YOUR GREEN FOLDER!!!
You have 5 minutes. IN YOUR SEATS. Paper and pencil out. Noise level 1. COMPLETE SENTENCES!!!
Write down the I CAN’s and Agenda if you finish early.

2. DNA mRNA What is transcription? Transcription: turns DNA into mRNA
mRNA: “messenger RNA” molecule that carries copy of genetic information
DNA
mRNA

3. Why do we use transcription?
DNA is coiled up in chromosomes
DNA cannot leave the nucleus because it is too important/fragile
Protein-making workshop, ribosomes, are outside the nucleus
 Have to turn DNA into something that CAN leave the nucleus.

4. Where does transcription happen?
In the Nucleus
Using genes, sections of DNA

5. How does transcription happen?
Helicase unzips DNA

6. How does transcription happen?
Helicase unzips DNA
RNA polymerase adds RNA nucleotides

7. How does transcription happen?
Helicase unzips DNA
RNA polymerase adds RNA nucleotides
Sugar-phosphate backbone is created

8. How does transcription happen?
Helicase unzips DNA
RNA polymerase adds RNA nucleotides
Sugar-phosphate backbone is created
mRNA separates from DNA

9. How does transcription happen?
Helicase unzips DNA
RNA polymerase adds RNA nucleotides
Sugar-phosphate backbone is created
mRNA separates from DNA
mRNA leaves the nucleus
for ribosomes

10. TRANSCRIPTION PRACTICE! DNA: A T T C A G A RNA: DNA: C C G A T T A G C
What about the Bases?
Notice anything strange here?
mRNA uses uracil (U) instead of thymine (T) !!
TRANSCRIPTION PRACTICE! DNA: A T T C A G A RNA: DNA: C C G A T T A G C
Go through the first example on the board and have students fill in the second one on their own

11. What is the product of transcription?
Practice Question #1
What is the product of transcription?

12. Why do we perform transcription? (Why can’t DNA leave the nucleus?)
Practice Question #2
Why do we perform transcription? (Why can’t DNA leave the nucleus?)

13. What are the reactants of transcription?
Practice Question #3
What are the reactants of transcription?

14. What happens first in transcription?
Practice Question #4
What happens first in transcription?

15. Practice Question #5
What happens after new nucleotides are added to the growing RNA strand?

16. What does RNA polymerase do?
Practice Question #6
What does RNA polymerase do?

17. What happens to RNA after it breaks from DNA?
Practice Question #7
What happens to RNA after it breaks from DNA?

18. A C T C C G A T A T A G Practice Question #8
Transcribe this DNA strand:
A C T C C G A T A T A G

19. Where does transcription happen? Why does it happen here?
Practice Question #9
Where does transcription happen? Why does it happen here?

20. Where will the mRNA go after it leaves the nucleus?
Practice Question #10
Where will the mRNA go after it leaves the nucleus?