1. Materials: 3 worksheets
Catalyst (5 min):
How did temperature affect the rate of a reaction as seen in our Gizmo?
What are 2 ways enzymes can be denatured?

2. Materials: 2 half sheets and paper from yesterday
Catalyst:
Identify the enzyme, substrate, and products in the following sentence.
A triglyceride is broken down into glycerol and fatty acids by lipase.

3. Elite Eight Trait Check-Up
Respect the Threshold
Everyone on time?
Silent for First Five?
Be Prepared (2 min)
Seated
Have materials
Working on catalyst

4. Unit 1 Class Point Challenge
Period 1: .77
Period 2: .88
Period 4: .90
Period 5: Winners!!!
Period 6: .37
Period 7: .76

5. Class Motto
If there is a problem, We look for a solution. If there is a better way, We find it. If we need help, We ask. If a teammate needs help, We give.

6. Announcements
We will be talking about Science and Engineering Expo Projects on Thursday/Friday. Come with research question (I have some of yours)
Enzymes Quiz Tomorrow
Enzymes project due
Thursday: Periods 1, 2, 4, 6
Friday: Periods 5, 7

7. Standard
SB1b. Explain how enzymes function as catalysts.

8. Recap Catalysts speed up chemical reactions.
Enzymes are catalysts in living things.
Catalysts and enzymes work by lowering the activation energy necessary for a reaction to occur.

9. EA is lowered by the enzyme
Red line: Rx catalyzed by enzyme

10. How are enzymes denatured?
Denatured = Destroyed
Enzymes are denatured by high temperatures and low pH (acids)

11. Collision Theory Gizmo
How did temperature affect the speed of molecules in the Gizmo?
How would this change the reaction?

12. So how would adding a catalyst affect the reaction?
Would it affect the speed of the molecules?
Would it affect the speed of the reaction?

13. Objectives
I can explain what it means for an enzyme to be specific, unchanged, and reusable.
I can recall the two ways enzymes are denatured.
I can identify the parts of an enzyme/substrate complex.
I can summarize the importance of enzymes in living organisms.

14. Notes 2.3: Enzymes and Catalysts
This is a continuation from last week! You may write on the same notes paper.

15. Enzymes Substrate: the material that an enzyme binds to
Enzyme-Substrate Complex: enzyme and substrate together
Active site: location where the substrate binds on the enzyme

16. Enzymes Enzymes often end in “ase” Lactase (breaks down lactose)
Helicase (unzips DNA)
Amylase (breaks down amylose)
Lipase (breaks down lipids)

17. Enzymes (Think – Pair – Share)
What’s a substrate?
What do enzymes usually end in?
Is lactase an enzyme or a substrate? How do you know?
What do you predict is the substrate for the enzyme sucrase?

18. Characteristics of Enzymes
Enzymes are:
Specific
Unchanged in a reaction
Reusable

19. Characteristics of Enzymes
Enzymes are specific:
They only work with one reaction
The enzyme and the substrate fit together like a lock and a key

20. Video
Think: How does this game show related to the characteristics of enzymes?

21. Characteristics of Enzymes
Question - does the substrate change? Does the enzyme change? Could the enzyme work again?

22. Or you might see it like this…
You will have to be ready to read a variety of different diagrams

23. Enzymes (Think – Pair – Share)
What is an enzyme?
What does it mean to say that enzymes are specific?
What does it mean to say that enzymes are reusable?
Why are enzymes important?

24. Enzymes What is structure X? What is structure Y? What is structure Z?
Walk through problem solving. Z is product. Step 2 is complex. Structure x changes, so can’t be enzyme!

25. Enzyme Disorders *LEL (Low Enzyme Levels) is America's & the world’s number one cause of sickness and death. *Inhibitors are molecules that decrease enzyme activity, and activators are molecules that increase activity. Drugs and poisons are often enzyme inhibitors.
Cystic Fibrosis
Gaucher's Disease
Low Stomach Acid
Inflammatory Bowel Disease/Syndrome
Intestinal Inflammation
Ulcerative Colitis
Ulcers
Acne
Gingivitis
Sprue
Pancreatic Insufficiency

26. Classwork 2.3: Enzymes
You will have 15 minutes to work on this assignment.
Graded for accuracy!

27. Enzymes Project
Objective: Manipulate enzyme cut outs to represent a chemical reaction in our body. Directions: 2 people at each table start with part A and 2 people start cutting. Then switch!

28. Panther Pass What do enzymes do?
What does it mean to say that enzymes are “specific”?
What are the 2 ways enzymes are denatured?
Which of the following statements best describes enzymes?
Enzymes cannot be reused after a reaction
Enzymes are organic catalysts
Enzymes slow down chemical reactions
Enzymes can bind to any substrate