1. Presented by: 1) Samar Magdy Mahmud 2) Sandy Haitham Roman

2. Sterilization What is Sterilization? Who needs to sterilize?
Some Products Requiring Sterility

3. What is sterilization? Definitions:
Sterilization: Process of killing or removing microorganisms from a product to insure that it is sterile

4. Medical Device Manufacturers
Who needs to sterilize?
Medical Device Manufacturers
Hospitals, Dentists, other health care facilities
Some specialty food product manufacturers

5. Some Products Requiring Sterility
Medical Devices
surgical gloves
clean room garments
syringes
surgical tools

6. sterilization
Chemical
GAS
LIQUID
Radiation
GAMMA RAYS
X-RAY’S
ULTRAVIOLET
Heat
STEAM
DRY

7. Heat Sterilization Advantages:
It is the simplest, most effective and inexpensive method.
There are 2 procedures depending on the tolerance of the material used:
Steam sterilization (Autoclaving)
Dry heat sterilization

8. Steam Sterilization Advantages: good penetration
maintains integrity of liquids (e.g. Lubricants) due to the 100% humidity within the chamber.
Disadvantages:
Non stainless steel metal items corrode
may damage plastic and rubber items
sharp instruments get dulled

9. Dry-Heat Sterilization
Involves heating at atmospheric pressure and often use a fan to obtain uniform temperature by circulation.
Heat at 180º for half hour , 170º for 1 hr., or 160º C for 2 hrs.
Times are the periods during which object is maintained at the respective temp.

10. Disadvantages: Less reliable than autoclaving
Large temp difference may arise within device.
sharp instruments get dulled
Many materials do nottolerate dry heat

11. Chemical Sterilization
The chemical compounds used can be:
a) Gas Sterilization :
The gas used in this procedure is ethylene oxide.
b) Liquid Sterilization:
Can be performed with buffered glutaric aldehyde.

12. Radiation Sterilization
Provides effective way of sterilization when used in high doses

13. Disadvantages: Posses threat to humans (radiation) Lengthy process
Requires very qualified personnel

14. THANK YOU