1. Chronic Glomerulonephritis
A progressive deterioration of renal function, which ends fatally in uremia and its complications unless dialysis / a kidney transplantation is performed.
Most cases are asymptomatic until later stages.

2. The course of chronic glomerulonephritis is variable.
In some pts, it progresses slowly and the loss of renal function is gradual.
In other pts, severe high blood pressure develops, which in turn hastens renal damage.
The renal changes consist of a thinning of the cortex, arterioscelerotic thickening of the renal arteries, and a progressive destruction of the glomeruli.
The kidney atrophies and renal function progressively decreases.

3. Etiology
Hypertension, prolonged and severe
Diabetes mellitus
Glomerulopathies (from lupus / other disorders)
Interstitial nephritis
Hereditary renal disease, polycystic disease
Obstructive uropathy
Developmental / congenital disorder

4. Clinical Manifestations
GI – anorexia, nausea, vomiting, hiccups, ulceration of GI tract , and hemorrhage
Cardiovascular – hyperkalemia, ECG changes, hypertension, pericarditis, pericardial effusion, pericardial tamponade
Respiratory – pulmonary edema, pleural effusions, pleural rub
Neuromuscular – fatigue, sleep disorders, headache, lethargy

5. Nursing Interventions Hemodialysis.
Peritoneal Dialysis.