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Figure 4. Levels of cerebrospinal fluid (CSF) immune and inflammatory markers in participants grouped by CSF human ... Figure 4. Levels of cerebrospinal.

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Presentation on theme: "Figure 4. Levels of cerebrospinal fluid (CSF) immune and inflammatory markers in participants grouped by CSF human ... Figure 4. Levels of cerebrospinal."— Presentation transcript:

1 Figure 4. Levels of cerebrospinal fluid (CSF) immune and inflammatory markers in participants grouped by CSF human ... Figure 4. Levels of cerebrospinal fluid (CSF) immune and inflammatory markers in participants grouped by CSF human immunodeficiency virus (HIV) ribonucleic acid (RNA) quantification and PC<sub>ratio</sub> status: CSF HIV RNA below the lower limit of quantification (<LOQ), F quantifiable CSF HIV RNA with PC<sub>ratio</sub> >1 (PC<sub>ratio</sub> >1), quantifiable CSF HIV RNA with PC<sub>ratio</sub> <1 (PC<sub>ratio</sub> <1). Median (middle line), interquartile range (extent of boxes), 1.5 times of interquartile range (whiskers), and outliers/extreme outliers (colored dots) are indicated. P value of non-parametric test between groups are shown. Dotted horizontal line: median level of 22 unmatched HIV-negative Thai controls. All markers level are presented in pg/mL. PC<sub>ratio</sub> = log<sub>10</sub> plasma HIV RNA minus log<sub>10</sub> CSF HIV RNA. Abbreviation: PC<sub>ratio</sub>, plasma-CSF HIV RNA ratio. Unless provided in the caption above, the following copyright applies to the content of this slide: © The Author(s) Published by Oxford University Press for the Infectious Diseases Society of America.This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence ( which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact J Infect Dis, Volume 218, Issue 6, 07 May 2018, Pages 937–945, The content of this slide may be subject to copyright: please see the slide notes for details.

2 Figure 3. Correlation between cerebrospinal fluid (CSF) and plasma human immunodeficiency virus (HIV) ribonucleic acid ... Figure 3. Correlation between cerebrospinal fluid (CSF) and plasma human immunodeficiency virus (HIV) ribonucleic acid (RNA) level by Fiebig staging. A level of 80 copies/mL was assigned to the CSF samples with HIV RNA level below quantification. Correlation coefficient = 0.719; P < .001 (Spearman). PC<sub>ratio</sub> = log<sub>10</sub> plasma HIV RNA minus log<sub>10</sub> CSF HIV RNA. Abbreviation: PC<sub>ratio</sub>, plasma-CSF HIV RNA ratio. Unless provided in the caption above, the following copyright applies to the content of this slide: © The Author(s) Published by Oxford University Press for the Infectious Diseases Society of America.This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence ( which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact J Infect Dis, Volume 218, Issue 6, 07 May 2018, Pages 937–945, The content of this slide may be subject to copyright: please see the slide notes for details.

3 Figure 2. Human immunodeficiency virus (HIV) ribonucleic acid (RNA) level by Fiebig stage (a) plasma and (b) ... Figure 2. Human immunodeficiency virus (HIV) ribonucleic acid (RNA) level by Fiebig stage (a) plasma and (b) cerebrospinal fluid (CSF). Median (solid line), interquartile range (extent of boxes), 1.5 times of interquartile range (whiskers), and outliers/extreme outliers (stars) are indicated. Number of participants by Fiebig stage (n): I (19); II (24); III (52); IV (15); V (7). A level of 80 copies/mL was assigned to those who had a CSF HIV RNA level below quantification. Unless provided in the caption above, the following copyright applies to the content of this slide: © The Author(s) Published by Oxford University Press for the Infectious Diseases Society of America.This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence ( which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact J Infect Dis, Volume 218, Issue 6, 07 May 2018, Pages 937–945, The content of this slide may be subject to copyright: please see the slide notes for details.

4 Figure 1. Cerebrospinal fluid (CSF) and plasma human immunodeficiency virus (HIV) ribonucleic acid (RNA) levels with ... Figure 1. Cerebrospinal fluid (CSF) and plasma human immunodeficiency virus (HIV) ribonucleic acid (RNA) levels with respect to days after estimated HIV exposure. A level of 80 copies/mL was assigned to those who had a CSF HIV RNA level below quantification. Unless provided in the caption above, the following copyright applies to the content of this slide: © The Author(s) Published by Oxford University Press for the Infectious Diseases Society of America.This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence ( which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact J Infect Dis, Volume 218, Issue 6, 07 May 2018, Pages 937–945, The content of this slide may be subject to copyright: please see the slide notes for details.

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