1. Do old pharmacokinetic parameter estimates predict new data?
B.J. Anderson, J. McLay, K. Allegaert, T. Engelhardt 
British Journal of Anaesthesia 
Volume 109, Issue 6, Pages (December 2012)
DOI: /bja/aes414
Copyright © 2012 The Author(s) Terms and Conditions

2. Fig 1
Prediction-corrected visual predictive check using parameter estimates from an earlier study5 and observations from the new study.2 All plots show the median and 90% intervals (solid and dashed lines). (a) shows all prediction-corrected observed concentrations. (b) shows prediction corrected percentiles (10%, 50%, and 90%) for observations (lines with symbols) and predictions (lines) with 95% confidence intervals for prediction percentiles (green-shaded areas).
British Journal of Anaesthesia  , DOI: ( /bja/aes414)
Copyright © 2012 The Author(s) Terms and Conditions