1. Nitric Oxide in Human Skin: Current Status and Future Prospects
Daniela Bruch-Gerharz , Thomas Ruzicka  
Journal of Investigative Dermatology 
Volume 110, Issue 1, Pages 1-7 (January 1998)
DOI: /j x
Copyright © 1998 The Society for Investigative Dermatology, Inc Terms and Conditions

2. Figure 1
Biosynthesis of NO. NO is generated by a class of NADPH-dependent NO synthases, which catalyze the conversion of arginine to citrulline and NO with a 1:1 stoichiometry. Three different isoenzymes have been characterized: two of them are constitutive and calcium-/calmodulin-activated (ecNOS and ncNOS), and one is an inducible, calcium-independent isoform (iNOS).
Journal of Investigative Dermatology  , 1-7DOI: ( /j x)
Copyright © 1998 The Society for Investigative Dermatology, Inc Terms and Conditions

3. Figure 2
Dual pathway mechanisms of NO. The formation of NO and the subsequent regulatory and cytotoxic effects of NO in the intracellular and extracellular milieu are listed.
Journal of Investigative Dermatology  , 1-7DOI: ( /j x)
Copyright © 1998 The Society for Investigative Dermatology, Inc Terms and Conditions

4. Figure 3
Potential functions of NO in human skin.Schematic model of a “generic” cell of the skin showing the potential targets and biologic functions of NO in human skin.
Journal of Investigative Dermatology  , 1-7DOI: ( /j x)
Copyright © 1998 The Society for Investigative Dermatology, Inc Terms and Conditions