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Cytogenetics Does Not Impact Outcomes in Adult Patients with Acute Lymphoblastic Leukemia Undergoing Allogeneic Hematopoietic Cell Transplantation Ibrahim Aldoss, Ni-Chun Tsai, Marilyn L. Slovak, Joycelynne Palmer, Joseph Alvarnas, Guido Marcucci, Stephen J. Forman, Vinod Pullarkat Biology of Blood and Marrow Transplantation Volume 22, Issue 7, Pages (July 2016) DOI: /j.bbmt Copyright © 2016 American Society for Blood and Marrow Transplantation Terms and Conditions
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Figure 1 OS, LFS, RI, and NRM of the whole cohort (n = 333). The 3-year OS, LFS, and RI were 55.7%, 47.9%, and 27.5%, respectively, and 1-year NRM was 17.3%. Biology of Blood and Marrow Transplantation , DOI: ( /j.bbmt ) Copyright © 2016 American Society for Blood and Marrow Transplantation Terms and Conditions
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Figure 2 The effect of remission status on alloHCT outcome. Patients who underwent alloHCT in CR1 had significantly better OS and LS, and lower RI, compared with those who underwent alloHCT in CR2 or other disease status. Biology of Blood and Marrow Transplantation , DOI: ( /j.bbmt ) Copyright © 2016 American Society for Blood and Marrow Transplantation Terms and Conditions
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Figure 3 The impact of cytogenetics on OS, LFS, RI, and NRM in the patients who underwent alloHCT in CR1 (n = 202). The 3-year OS, LFS, and RI were 69.8%, 62.3%, and 17.1% respectively, and 1-year NRM was 13.3%. Poor-risk cytogenetics did not significantly impact OS or LFS, but was associated with increased RI. Biology of Blood and Marrow Transplantation , DOI: ( /j.bbmt ) Copyright © 2016 American Society for Blood and Marrow Transplantation Terms and Conditions
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