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Pietro Santulli, M. D. , Bruno Borghese, M. D. , Ph. D

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Presentation on theme: "Pietro Santulli, M. D. , Bruno Borghese, M. D. , Ph. D"— Presentation transcript:

1 Interleukin-19 and interleukin-22 serum levels are decreased in patients with ovarian endometrioma 
Pietro Santulli, M.D., Bruno Borghese, M.D., Ph.D., Sandrine Chouzenoux, Isabelle Streuli, M.D., Didier Borderie, M.D., Ph.D., Dominique de Ziegler, M.D., Bernard Weill, M.D., Ph.D., Charles Chapron, M.D., Frederic Batteux, M.D., Ph.D.  Fertility and Sterility  Volume 99, Issue 1, Pages e2 (January 2013) DOI: /j.fertnstert Copyright © 2013 American Society for Reproductive Medicine Terms and Conditions

2 Figure 1 Serum IL-19 and IL-22 levels measured by ELISA in patients with OMA and in controls not including undetectable levels. IL-19 concentration was lower in women with endometrioma (n = 21) than in controls (n = 19; P=.006). Serum IL-22 concentrations between endometrioma (n = 51) and controls (n = 54) were significantly different (P<.001). Statistical analysis was performed using the Mann-Whitney U-test. Serum IL values are presented on a logarithmic scale as median with interquartile range. Fertility and Sterility  , e2DOI: ( /j.fertnstert ) Copyright © 2013 American Society for Reproductive Medicine Terms and Conditions

3 Figure 2 Correlation between serum IL levels and clinical parameters of endometriosis. (A) Correlation between IL-19 and deep dyspareunia. (B) Correlation between IL-22 and deep dyspareunia. (C) Correlation between IL-22 and NCCPP. Spearman's rank correlation test was used to assess correlations. Fertility and Sterility  , e2DOI: ( /j.fertnstert ) Copyright © 2013 American Society for Reproductive Medicine Terms and Conditions


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