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Human Skin Explants Recapitulate Key Features of HSV-1 Infections

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Presentation on theme: "Human Skin Explants Recapitulate Key Features of HSV-1 Infections"— Presentation transcript:

1 Human Skin Explants Recapitulate Key Features of HSV-1 Infections
Megan H. Orzalli  Journal of Investigative Dermatology  Volume 139, Issue 3, Pages (March 2019) DOI: /j.jid Copyright © 2018 The Author Terms and Conditions

2 Figure 1 HSV-1 productively infects abdominal skin after perturbation with a microneedle roller. HSV-1 infection results in decreased nectin 1 expression and increased accumulation of nuclear NF-κB and IRF3. Virus replication in the skin is inhibited by antiviral drugs. HSV-1, herpes simplex virus type 1. Journal of Investigative Dermatology  , DOI: ( /j.jid ) Copyright © 2018 The Author Terms and Conditions


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