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Enzymes
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What Are Enzymes? Enzymes are Proteins
Act as Catalyst to speed up chemical reactions
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Enzymes Are specific for what they catalyze Are Reusable End in –ase
-Sucrase -Lactase -Maltase
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How do enzymes Work? Enzymes weaken chemical bonds which lowers activation energy (the energy needed to start a reaction)
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Enzymes Without Enzyme With Enzyme Free Energy
Progress of the reaction Reactants Products Free energy of activation
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Enzyme-Substrate Complex
The substance an enzyme acts on is the substrate Enzyme Joins Substrate
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Active Site A restricted region on an enzyme molecule that binds to the substrate. Active Site Enzyme Substrate
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What Affects Enzyme Activity?
Two factors: 1.Environmental Conditions 2.Enzyme Inhibitors
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1. Environmental Conditions
1. Extreme Temperatures are the most dangerous - high temps denature (unfold) the enzyme. (globular chain) 2. pH (most like 6-8 pH near neutral)
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2. Two examples of Enzyme Inhibitors
a. Competitive inhibitors: attaches to the active site and blocks substrate Enzyme Substrate Competitive inhibitor
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Inhibitors b. Noncompetitive inhibitors:
binds to another part of the enzyme changes the active site. Enzyme Noncompetitive Inhibitor Substrate active site altered
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