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Component-resolved in vitro diagnosis of hazelnut allergy in Europe
Kirsten Skamstrup Hansen, MD, PhD, Barbara K. Ballmer-Weber, MD, PhD, Joaquin Sastre, MD, PhD, Jonas Lidholm, PhD, Kerstin Andersson, PhD, Hubert Oberhofer, MD, Magdalena Lluch-Bernal, MD, Jonas Östling, PhD, Lars Mattsson, PhD, Frauke Schocker, PhD, Stefan Vieths, PhD, Lars K. Poulsen, PhD Journal of Allergy and Clinical Immunology Volume 123, Issue 5, Pages e3 (May 2009) DOI: /j.jaci Copyright © 2009 American Academy of Allergy, Asthma & Immunology Terms and Conditions
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Fig 1 Level of IgE for all hazelnut allergens. The y axis represents the common log scale. Hatched lines indicate cutoff values at 0.1 and 0.35 kUA/L. The number of values of less than 0.1 kUA/L is indicated for each plot. The median value for each data set is marked by a short horizontal line. Lines at the top show significant differences (P ≤ .05). HN, Patients with hazelnut allergy; Po, control subjects with pollen allergy; DK, Denmark; CH, Switzerland; E, Spain. Journal of Allergy and Clinical Immunology , e3DOI: ( /j.jaci ) Copyright © 2009 American Academy of Allergy, Asthma & Immunology Terms and Conditions
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Fig 2 Receiver operating characteristic curves of sensitivity and specificity of IgE analyses at different cutoff levels: 0.1, 0.35, 0.7, 3.5, and 17.5 kUA/L. Sensitivity is shown along the y-axis, and 1-specificity is shown along the x-axis. Dashed lines represent the nonatopic control group, and dotted lines represent the control subjects with pollen allergy. The solid line indicates x = y. CH, Switzerland; DK, Denmark; E, Spain. Journal of Allergy and Clinical Immunology , e3DOI: ( /j.jaci ) Copyright © 2009 American Academy of Allergy, Asthma & Immunology Terms and Conditions
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