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sm“FISH”ing for Hedgehog

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Presentation on theme: "sm“FISH”ing for Hedgehog"— Presentation transcript:

1 sm“FISH”ing for Hedgehog
Michael L. Drummond, Scott X. Atwood  Journal of Investigative Dermatology  Volume 137, Issue 1, Pages (January 2017) DOI: /j.jid Copyright © 2016 The Authors Terms and Conditions

2 Figure 1 Hh gradient in wild-type and Ptch1;Ptch2-deficient hair follicles. (a) Graded Hh response in a developing hair follicle with peak, intermediate, and low levels of Hh target gene induction. Cellular markers of each zone listed to the left. (b) K5Cre:Ptch1lox/lox;Ptch2tm1/tm1-deficient skin displays only peak Hh activation throughout developmentally delayed hair follicles and hyperproliferative skin. Hh, Hedgehog; Ptch, patched. Journal of Investigative Dermatology  , 13-15DOI: ( /j.jid ) Copyright © 2016 The Authors Terms and Conditions


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