1. Carcinoma of the Stomach With Hepatocyte Differentiation (Hepatoid Adenocarcinoma) 
Catherine C. Roberts, M.D., Thomas V. Colby, M.D., Kenneth P. Batts, M.D. 
Mayo Clinic Proceedings 
Volume 72, Issue 12, Pages (December 1997)
DOI: /
Copyright © 1997 Mayo Foundation for Medical Education and Research Terms and Conditions

2. Fig. 1
Hepatoid gastric adenocarcinoma. Gross formalin-fixedx sections of stomach show ulcerated mass involving submucosa and muscularis propria. Greenish hue in multiple regions correlates with histologic finding of bile production.
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3. Fig. 2
Hepatoid gastric adenocarcinoma. Hepatoid foci show trabecular growth pattern with abundant eosinophilic cytoplasm and central nuclei typical of hepatocytes. Cells form rosettes around bile canaliculi, which contain bile plugs {arrows). (Hematoxylin-eosin.)
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4. Fig. 3
Hepatoid gastric adenocarcinoma. Hepatoid tumor cells show pale juxtanuclear vacuoles (“pale bodies” [arrows]) (left, hematoxylin-eosin), which stained strongly with polyclonal antibodies to carcinoembryonic antigen (right).
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5. Fig. 4
Hepatoid gastric adenocarcinoma. In some regions, hepatoid foci (top) merged with more conventional intestinal-type acinar adenocarcinoma (lower center, arrows). Hematoxylineosin.)
Mayo Clinic Proceedings  , DOI: ( / )
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