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Infertility Management and Referral
Laura Neale
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History and Examination
Unprotected sex 1 year (unless known problems) Primary or secondary Predisposing factors Menstrual cycle STIs Previous ectopics Galactorrhoea/hirsutism/acne Systemic diseases Drug history (NSAIDs, chemotherapy, neuroleptics) Lifestyle factors BMI Features of PCOS
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Investigations (1) Anovulatory Male factor Unexplained Tubal Other
Think in terms of cause Anovulatory Male factor Unexplained Tubal Other
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Investigations (2) Day 2-5 FSH and LH Day 21 progesterone
Semen analysis Rubella screen Chlamydia screen
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Investigations (3) If anovulatory
TFTs Prolactin Oestradiol Testosterone SHBG Assess tubal status (unless semen analysis abnormal)
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Counselling Optimise weight Usual lifestyle advise Folic acid
Investigative course Costs (emotional and financial) Chances failure (i.e. only 15% success rate per IVF cycle if age > 36)
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