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A Randomized Phase II Study of Gemcitabine and Carboplatin with or without Cediranib as First-Line Therapy in Advanced Non–Small-Cell Lung Cancer: North.

Published byEmine Gonca Ekinci Modified over 5 years ago

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Presentation on theme: "A Randomized Phase II Study of Gemcitabine and Carboplatin with or without Cediranib as First-Line Therapy in Advanced Non–Small-Cell Lung Cancer: North."— Presentation transcript:

1 A Randomized Phase II Study of Gemcitabine and Carboplatin with or without Cediranib as First-Line Therapy in Advanced Non–Small-Cell Lung Cancer: North Central Cancer Treatment Group Study N0528  Grace K. Dy, MD, Sumithra J. Mandrekar, PhD, Garth D. Nelson, MS, Jeffrey P. Meyers, BA, Araba A. Adjei, PhD, Helen J. Ross, MD, Rafat H. Ansari, MD, Alan P. Lyss, MD, Philip J. Stella, MD, Steven E. Schild, MD, Julian R. Molina, MD, PhD, Alex A. Adjei, MD, PhD  Journal of Thoracic Oncology  Volume 8, Issue 1, Pages (January 2013) DOI: /JTO.0b013e318274a85d Copyright © 2012 International Association for the Study of Lung Cancer Terms and Conditions

2 FIGURE 1 CONSORT trial flow diagram.
Journal of Thoracic Oncology 2013 8, 79-88DOI: ( /JTO.0b013e318274a85d) Copyright © 2012 International Association for the Study of Lung Cancer Terms and Conditions

3 FIGURE 2 Kaplan–Meier curves in overall population for (A) progression-free survival and (B),overall survival. Journal of Thoracic Oncology 2013 8, 79-88DOI: ( /JTO.0b013e318274a85d) Copyright © 2012 International Association for the Study of Lung Cancer Terms and Conditions

4 FIGURE 3 Kaplan–Meier curves for overall survival according to polymorphic variants A, FGFR1 rs , (B) FGFR2 rs , and (C) VEGFR3 rs Journal of Thoracic Oncology 2013 8, 79-88DOI: ( /JTO.0b013e318274a85d) Copyright © 2012 International Association for the Study of Lung Cancer Terms and Conditions

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